It is apparent that inflammation is a major force behind both Multiple Sclerosis Disease (MSD) and CardioVascular disease (CVD).  During Multiple Sclerosis Disease exacerbations, inflammation is even more apparent; and likewise during cardiovascular events.  Also, patients with persistent inflammation have a poorer outcome.  Moreover, both Multiple Sclerosis Disease and CardioVascular Disease are made worse by psychological stress as well as oxidative stress.  Bridging the intervention gap between MSD and CVD may occur when inflammation, among other things, is addressed through healthy lifestyle measures. See references below.


1. Immunology. 2010 Feb;129(2):154-69.  Inflammation in neurodegenerative diseases.

Amor S, Puentes F, Baker D, van der Valk P.

2. J Neurol Sci. 2011 Jul 15;306(1-2):167-9. Epub 2010 Aug 16.

Pathophysiology of inflammation and tissue injury in multiple sclerosis: what are the targets for therapy.

Lassmann H.

3. J Cardiol. 2009 Jun;53(3):317-33. Epub 2009 Jan 29.

Inflammatory biomarkers in coronary artery disease.

Zakynthinos E, Pappa N.

4. Brain Nerve. 2008 Feb;60(2):157-70.

The role for oxidative stress in neurodegenerative diseases

Shibata N, Kobayashi M.

5. Pol Merkur Lekarski. 2009 Dec;27(162):499-502.

Oxidative stress in multiple sclerosis

Miller E, Mrowicka M, Zo?y?ski K, Kedziora J.

6. Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):29-38. Epub 2004 Nov 11.

Oxidative stress and vascular disease.

Madamanchi NR, Vendrov A, Runge MS.

7. PLoS One. 2011 Jan 13;6(1):e16149.

Smoking and multiple sclerosis: an updated meta-analysis.

Handel AE, Williamson AJ, Disanto G, Dobson R, Giovannoni G, Ramagopalan SV.

8. Chest. 2009 Jul;136(1):212-9. Epub 2009 Feb 18.

A pilot study to examine the effects of smoking cessation on serum markers of inflammation in women at risk for cardiovascular disease.

Reichert V, Xue X, Bartscherer D, Jacobsen D, Fardellone C, Folan P, Kohn N, Talwar A, Metz CN.

9. JAMA. 2003 Mar 26;289(12):1533-6.

Multiple sclerosis and Epstein-Barr virus.

Levin LI, Munger KL, Rubertone MV, Peck CA, Lennette ET, Spiegelman D, Ascherio A.

Am J Pathol. 2009 Jul;175(1):440-7.

10. Epstein-barr virus-induced gene-3 is expressed in human atheroma plaques.

Kempe S, Heinz P, Kokai E, Devergne O, Marx N, Wirth T.

11. Angiology. 2010 Feb-Mar;61(1):31-6. Epub 2009 Jun 3.

Arterial compliance in multiple sclerosis: a pilot study.

Fjeldstad C, Frederiksen C, Fjeldstad AS, Bemben M, Pardo G.

12. Heart Dis. 2000 Sep-Oct;2(5):375-9.

On arterial physiology, pathophysiology of vascular compliance, and cardiovascular disease.

Glasser SP.

13. Mind Brain. 2011 Aug;2(1):32-37.

Anxiety and cardiovascular risk: Review of Epidemiological and Clinical Evidence.

Olafiranye O, Jean-Louis G, Zizi F, Nunes J, Vincent M.

14. Mult Scler. 2008 Nov;14(9):1262-8. Epub 2008 Aug 28.

Influence of anxiety and reported stressful life events on relapses in multiple sclerosis: a prospective study.

Potagas C, Mitsonis C, Watier L, Dellatolas G, Retziou A, Mitropoulos P, Sfagos C, Vassilopoulos D.

15. Future Cardiol. 2009 Jul;5(4):333-42.

Astaxanthin, oxidative stress, inflammation and cardiovascular disease.

Fassett RG, Coombes JS.

What can be done?

  1. Vitamin D3     5,000 iu daily
  2. Astaxanthin    5 mg daily

To Your Better Health

Dr. Rudy Cartwtight, MS Health Coach

PS:  Post your comments.  Let me hear from you.

18 thoughts on “BRIDGING THE MSD & CVD GAP

  1. heya doctor rudy i want to thank you for this information ive lerned more from you and your website than any other doctor. all they tell you is here take this or try this ohh and they cost 1000’s a month and your insurance dosent cover them i’am a peron with secondary progessive ms and it realy sucks and ive had multiple operations on my knees to lumbar fusion and the list goes on but these operations mixed with ms meens things are tuff for me but we do ty for all the info

  2. In your opinion doctor…
    which is better and more useful fingolimod or Avonex?
    i hope i can get an answer…

  3. Hello Dr. Cartwtight –

    May God bless you for all your hard work! Words cannot express, properly, my gratitude. I am working on addressing stress. It is difficult. I am totally dependent BUT am a “FIGHTER!”

    My thanks,

  4. HI: It has been my experience that hyperbaric oxygen therpy (HBOT) has been very effectivr in treatment of MS. Over 80% with HBOT have had significant decrease in their MS symptoms and I have patients that have complete reversal of symptoms at up to 30 + years. Why is data about the value of HBOT in MS not availabe to the MS pateint? Let me know if ?s. wsm md

  5. Hi,

    I have the opportunity to have a stem cell transplant for MS. Do you have any comments positive or negative. Please help me navigate these waters.

  6. I appreciate so much that there r people like u with such compassion, experience & the wisdom 2 share your very valuable knowledge with people like me living with MS, I thank GOD that i’ve founf u & i ask him 2 continually bless u. Can u tell me what xactly is “oxidative stress” because i use CELL food h2o product, 6 drops 2wice a day, should i continue & what is Astaxanthin & where can i buy it? Thank u Sincerely,

  7. my brother aged 55 has m s and he is getting far worse he is unsteady on his feet and can only walk a short distance about 100 meters with the aid of a walking stick untill he is out of breath . is there anything he could try to give him more strenght to walk . the way he is going it looks like he could be in a wheelchair soon.
    yours david bennett

  8. Hi Dr. Cartwright

    I was diagnosed with MS about 3 years ago. I also have spinal stenosis. I have had C4/5 and 5/6 fusions. I am now having a great deal of sciatic pain. I have been taking the essentials and Vitamin D3 religiously. I just received Sue Ellen’s book with recipes. I am on sooo much medication that it really worries me. Do you have any suggestions for me that might help?

    Thank you very much for all that you do.

    Virginia Labelle

  9. Dr. Cartwright,
    I have developed ringing in my ear, more like a hissing. Is there anything I can do for that?

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.